To obtain a lightweight and high-strength wood sandwich structure, a wooden lattice sandwich cell element was designed in combination with a pyramid-type structure. After inserting glue to prepare the cell unit, the influence of panel thickness and core diameter on the unit cell force was analyzed and compared under the condition of flat pressure. Under the condition of flat pressure, the specific strength of the unit cell was higher than that of the specific strength of the composition material, and the unit cell may be regarded as a structure with high specific strength. Theoretical predictions, simulation analysis, and experimental tests demonstrated that the structure compressive capacity depended on the diameter of the core when the core length was set. The larger the diameter of the core is, the stronger the bearing capacity of the unit cell will be. When the diameter of the core is constant, the longer the core length is, the weaker the bearing capacity of the unit cell will be. The simulation analysis was in agreement with the experimental test results, indicating that the destruction of the structure was mainly caused by the failure of the core.