AbstractThe use of formaldehyde-free, biomass-based composites has gained increasing attention in recent years because of their environmental benefits and superior strength properties. In this study, oriented cotton stalk board (OCB) was fabricated with an environmentally friendly, water-based konjac glucomannan-chitosan-polyvinyl alcohol (KCP) blend adhesive using hot pressing technology. The effects of pressing parameters on the physical and mechanical properties of oriented cotton stalk board were examined in order to obtain optimal pressing parameters. Interfacial bonding surface was also examined with a scanning electron microscope and a fluorescence microscope. The optimal physical and mechanical properties were obtained at a pressing temperature of 150 °C for 15 min with a target density of 0.8 g/cm3 during hot pressing. Adhesive content and hot pressing pressure had significant influences on adhesion. Mechanical interlocking was also observed between cotton stalks and the adhesive. OCB with KCP blend adhesive has comparable mechanical properties to that with urea formaldehyde resin or phenolic formaldehyde resin. OCB resinated with KCP blend adhesive is environmental friendly and has potential applications in furniture and interior decoration with less stringent requirements for water resistance.