AbstractThe pyrolysis of tobacco residue in the presence of metal oxides and metal chlorides was investigated at 300, 400, and 500 °C. Catalysts used were Al2O3, Fe2O3, AlCl3, and SnCl4 in concentrations from 1 up to 5 wt% of the tobacco residue feedstock. The amount of catalysts and the pyrolysis temperature had significant effect on both product distributions and bio-oil composition. The catalytic effect was dominant at the lowest temperature (300 °C). The pyrolysis temperature was decreased by 200 °C compared to the thermal run. Bio-oil contained a large variety of compounds. Nicotine, which is very stable until temperatures in excess of 600 °C, could be degraded at the lowest temperature by using 1 wt% of AlCl3 and 1 wt% of Fe2O3.