Today, the toilet paper market offers product types with varying number of plies, providing better mechanical strength and liquid absorption. Several tissue paper perforation systems exist, and the best commonly applied is a top-cutting mechanism that includes an oblique blade, a combined oblique blade, or a simple spiral blade. The perforation efficiency must be high to have an easy sheet separation from the roll of the toilet paper, which does not always occur. Hence, consumer satisfaction can depend on the perforation performance. To study this, a laboratory perforation system was used to perforate different commercial toilet papers (in brands and number of plies) and evaluate their perforation efficiency. A finite element method (FEM) was used to simulate the curve of the progression of perforation efficiency as a function of the cut distance. The main findings were a stabilization of the perforation efficiency from a cut distance of 6 mm and a 15% increase in the cut distance for the laboratory blade to match the industrial perforation efficiency. The FEM analysis confirmed the behavior of the evolution of perforation efficiency with the increase of the cut distance.